Nowadays, with asymmetric economies in the world of globalism, with uncertainty, lack of trust and continuous struggle for exploitation οf natural sources and energy supplies, tensions increase, under the pressure of serious economic difficulties, which need new solutions and approaches. In this international economic environment, considering the creation of economic value a primary need for all companies and management the complex procedure of achieving it, we focus on systematic methodologies approach, analyzing the most important components in business strategies, whilst continuously looking for innovative ideas and adaptation of procedures to regional needs.